Dr Briony Larance is an NHMRC Australian Public Health Early Career Fellowship recipient and has worked at the National Drug and Alcohol Research Centre (NDARC), Faculty of Medicine, UNSW, since 2004. Her research interests include opioid dependence, opioid substitution therapy and pharmaceutical opioids. Her research focuses on understanding the trajectories and health consequences of pharmaceutical opioid use among diverse populations, including chronic pain patients and people who are opioid dependent and/or inject drugs. She has been involved in epidemiological and clinical studies utilising a range of methods, including randomised-controlled trials, post-marketing surveillance studies, analyses of linked administrative data and cohort studies. Current research projects include a large cohort study of patients being prescribed opioids for non-cancer pain; post-marketing surveillance studies of a tamper-resistant formulation of oxycodone; piloting interventions to improve the treatment of pain and the prescribing of pharmaceutical opioids in general practice; and a multi-site collaboration examining the pharmacoepidemiology of opioid use in Australia.