2C. HIV&AIDS Abstract Session: Discovery and Translational Science: Immunotherapy approaches for HIV cure
Tracks
Track 3
Monday, September 15, 2025 |
11:00 AM - 12:30 PM |
City Room 3&4 (Upper Level) |
Details
All Abstract Presenter Q&A at the end of the session.
Speaker
Prof Boro Dropulic
Executive Director of Caring Cross and CEO of Vector BioMed at Gaithersburg
BioMed
Affordable access of cellular gene therapies and the development of a CAR-T cell therapy for HIV (Virtual Presentation)
11:00 AM - 11:30 AMBiography
Boro received his PhD from the University of Western Australia and his MBA from the Johns Hopkins University (JHU). He has been in the gene therapy field since the late 1980s.
After a Fogarty Fellowship at the NIH, he joined the faculty at JHU where he worked on developing Lentiviral vectors as delivery systems for gene therapy. After 4 years in academia, he founded his first company ViRxSys and led the team that first demonstrated the safety of Lentiviral vectors in humans with his UPenn colleagues. Later he founded Lentigen, which first developed the Lentiviral vector used to produce Kymriah®, the first FDA-approved gene therapy product.
Later, Boro saw an opportunity to integrate Lentiviral vector technology with closed-system automated cell processing devices to enable distributive place-of-care manufacturing at hospitals, potentially improving the affordability and accessibility of gene therapy products like CAR-T cells. He therefore spearheaded the acquisition of Lentigen by Miltenyi Biotec in 2014 and led the development of a global place-of-care network of clinical centers that were able to successfully manufacture CAR-T cell products and demonstrate their therapeutic benefits in clinical trials.
Seeing a need for improved business models to support the affordability and accessibility of gene therapy products, Boro co-founded Caring Cross a 501 (c)(3) non-profit and serves as the Executive Director. He also is the CEO of Vector BioMed, a public benefit corporation that was spun-out of Caring Cross to provide affordable GMP Lentiviral vector manufacturing services to the gene therapy scientific community.
Dr Hannah King
Research Fellow
Doherty Institute
HIV-specific T cells in PWH following immune checkpoint blockade"
11:30 AM - 11:50 AMBiography
Dr Hannah King completed her PhD at the Burnet Institute in 2018, investigating the antigenicity and immunogenicity of novel HIV vaccine candidates. From there, she moved to the US for a postdoctoral appointment jointly between the National Institutes of Health and the U.S. Military HIV Research Program, focused on assessing the efficacy of HIV cure and vaccine strategies in non-human primate models. In 2024 she returned to Melbourne to take a position as a Research Officer in Sharon Lewin's lab, where she is investigating the immunological impacts of novel HIV cure interventions in clinical trials.
Prof James Mcmahon
ID Physician
Alfred Health
Safety of Low dose Nivolumab in Adults with HIV on Antiretroviral therapy: The NIVO-LD Trial
11:50 AM - 12:02 PMBiography
Professor James McMahon is Head of the Infectious Diseases Clinical Research Unit at the Alfred Hospital, Melbourne and an ID physician at the Alfred, and Monash Medical Centre. He is the current ASHM President with research interests in clinical trials for HIV Cure, antiretroviral therapy, and COVID-19 prevention and treatment
A/Prof Anna Hearps
Research Scientist
Burnet Institute
Targeted elimination of HIV-infected cells using antibody-dependent cellular cytotoxicity
12:02 PM - 12:14 PMBiography
A/Prof Hearps is a Co-Director of the Disease Elimination program and a laboratory head at the Burnet Institute in Melbourne. Her research group investigates HIV reservoirs and cure approaches as well as mechanisms of increased comorbidity risk in people with HIV.
Associate Professor Najla Nasr
Head Of The Hiv Immunotherapeutic Lab
Westmead Institute For Medical Research, University of Sydney
Eradicating HIV using CD8 CAR T cells
12:14 PM - 12:26 PMBiography
Associate Professor Nasr leads the HIV Immunotherapeutic Lab aiming at developing therapeutics for the eradication of chronic HIV. Her second area of research focuses on investigating sexual transmission of HIV using the actual human anogenital tissues where infection occurs to prevent HIV transmission.
HIV&AIDS Conference
2C. Questions & Discussion
12:26 PM - 12:30 PMBiography
HIV&AIDS Session Chair
Thomas Angelovich
Senior Lecturer
RMIT University
Sushama Telwatte
Locarnini Fellow In Virology
Doherty Institute
