Theme A Session 5: Tissue issues: Interactions between HIV, Target cells and Immune responses in tissues
Tracks
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Tuesday, September 25, 2018 |
4:30 PM - 6:00 PM |
Tuscan (Ground Floor) |
Details
Learning Objectives: 1) To define how HIV interacts with its target cells during sexual transmission 2) To define the HIV reservoirs with intestinal tissue
Speaker
Professor Barbara Shacklett
Professor
University of California, Davis
A Closer Look at HIV-Specific T-cells in Mucosal Tissues
4:30 PM - 5:00 PMBiography
Dr Barbara Shacklett, PhD, is Professor of Microbiology and Immunology at the University of California, Davis. Her laboratory is recognized for developing and applying innovative approaches to study mucosal immunity to HIV. Over the past 10 years, her work has helped elucidate the relationship between mucosal T-cell responses and immune control of HIV infection, both in human cohorts and in the nonhuman primate model (SIVmac). This work has included studies of HIV “Elite” Controllers, the role of mucosal regulatory T-cells (Treg), mucosal immune reconstitution in individuals on combination antiretroviral therapy (cART), and mucosa-associated invariant T-cells (MAIT cells). Her group also studies the female reproductive tract, including hormonal regulation of innate and adaptive immune responses and the impact of menstrual cycle phases on host defense. She has coauthored over 80 peer-reviewed publications, served on grant review panels in the US, France, and Canada, and is currently an Associate Editor of Mucosal Immunology.
Dr Jenny Anderson
Senior Scientist
Doherty Institute
Rectal CCR6+ CD4+ T-Cells Are An Important Reservor In HIV-Infected Individuals On Art
5:00 PM - 5:15 PMBiography
Dr Jenny Anderson is a Senior Scientist in Prof Sharon Lewin and Assoc Prof Paul Cameron's laboratory at the Doherty Institute at the University of Melbourne. Since 2012, she has studied HIV persistence in resting CD4+ T-cell subsets in HIV+ individuals on ART and new strategies to purge persistent HIV.
Mr Heeva Baharlou
Phd Candidate
The Westmead Institute For Medical Research
Associate Professor James McMahon
Head of Clinical Research Unit
Alfred Health
Developing Strategies To Image HIV In Vivo: Combining The Sarcophagine Chelator Mecosar To 3BNC117 Does Not Affect HIV Binding Or Neutralisation
5:30 PM - 5:45 PMBiography
Dr McMahon is an Infectious Diseases physician and Head of Clinical Research at the Alfred Hospital, an ID physician at Monash Medical Centre and Chairs the ASHM ARV Guidelines Committee. His research interests are in HIV Cure-focused clinical trials, antiretroviral therapy and methods to maximise retention in HIV care.
Dr Jennifer Zerbato
Post-doctoral Research Fellow
Doherty Institute For Infection And Immunity
HIV Persistence In Lymph Node Tissue And Peripheral Blood: The Role Of Immune Checkpoints
5:45 PM - 6:00 PMBiography
Dr. Jennifer Zerbato is a post-doctoral research fellow in the laboratory of Professor Sharon Lewin and Associate Professor Paul Cameron. Dr. Zerbato’s research is primarily focused on HIV latency reversal strategies as well as new strategies to identify and characterize the HIV latent reservoir in individuals on ART.
Chair
Kirstie Bertram
Post-doctoral Scientist
Westmead Insitute For Medical Research
Andrew Harman
Group Leader
The University of Sydney